Last Updated Dec 2008

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Acute Myelogenous Leukemia Diagnosis

It is very difficult to distinguish AML from ALL based only on presenting signs and symptoms
Like ALL, the CBC typically reveals anemia, thrombocytopenia, and a WBC count that may be high, low, or normal
Auer rods seen on peripheral smear are pathognomonic for AML
Bone marrow aspirate is diagnostic: > 30% of cells are nonlymphoid blasts
Blood type/HLA typing for possible treatment
Lumbar puncture in symptomatic AML patients and all ALL patients
The FAB (French-American-British) classification divides AML into subtypes (M0 – M7) based on morphologic and histochemical information